We aim to understand the morphogenesis, homeostasis and disease pathogenesis of lymphatic vessels and blood vessels and their microenvironments to provide new strategies for regenerative medicine and treatment of immune diseases, cancer, and edema. To this end, we are working to develop novel three-dimensional (3D) organ-on-chip systems, cellular and molecular tools, and in vivo models to better understand the mechanisms by which cells regulate and respond to biological and mechanical cues.

Recent News


December 2, 2021:

Isabelle awarded the Alan D. Mathios Research & Service Grant. Congratulations!!


November 6, 2021:

Ania’s insightful commentary on lymphatic co-culture model and cancer is now published in EBioMedicine (Lancet). Congratulations, Ania!


October 28, 2021:

Harry and Samantha join the lab as Ph.D. students. Welcome!


October 5, 2021:

Dr. Lee gives a seminar at Johns Hopkins BME on October 11, 2021.


October 4, 2021:

New paper is out: A bioengineered lymphatic vessel model for studying lymphatic endothelial cell-cell junction and barrier function by Henderson et al! This study received Microcirculatory Society Award for Excellence in Lymphatic Research 2021!

The paper is also selected as a journal cover!


September 30, 2021:

Cort’s proposal titled “Control of Cytotoxic T cell Mechanosensing by Piezo 1” has been selected to receive a Fall 2021 research award from Cornell Engineering Learning Initiative (ELI). Congratulations, Cort!


September 23, 2021:

Lab awarded NIH R21 grant from NIAID! We look forward to exploring immune cell interactions with lymphatics in collaboration with Dr. Deborah Fowell.


June 8, 2021:

Meera’s proposal titled “Modeling Breast Cancer Metastasis with Bioengineered Tumor-on-Chip Platform” has been selected to receive a Summer 2021 research award from Cornell Engineering Learning Initiative (ELI). Congratulations, Meera!


June 1, 2021:

Cort awarded the Sigma Xi Award. Congratulations, Cort!  



To create and nurture a diverse community dedicated to discovery, scholarship, and leadership to improve human health and wellness by taking principles from engineering, biology, and medicine” – Lee lab mission.



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