We aim to understand the morphogenesis, homeostasis, and disease pathogenesis of lymphatic vessels and blood vessels and their microenvironments to provide new strategies for regenerative medicine and treatment of immune diseases, cancer, and edema. To this end, we are working to develop novel three-dimensional (3D) organ-on-chip systems, cellular and molecular tools, and in vivo models to better understand the mechanisms by which cells regulate and respond to biological and mechanical cues.
Recent News

September 10, 2024:
Check out Dr. Lee’s talk at the Lymphatic Education & Research Network (LE&RN) online symposium
August 29, 2024:
March 25, 2024:
Check out our collaborative work with Dr. Young-Kwon Hong from USC, published in Nature Neuroscience! In this study, Renhao demonstrated how Piezo1 controls fluid drainage using lymphatics-on-chip, offering a new idea to address excessive CSF buildup in the brain!
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“To create and nurture a diverse community dedicated to the discovery, scholarship, and leadership to improve human health and wellness by taking principles from engineering, biology, and medicine” – Lee lab mission.