We look for highly motivated postdoctoral fellows, graduate students (Ph.D., M.S.), undergraduate students and technicians. We broadly study lymphatic and vascular biology, cancer biology, immunoengineering, and regenerative medicine by employing 3D organs-on-chip in vitro platforms, molecular biology methods, and in vivo animal models. We encourage open-minded persons from different backgrounds (e.g., biology, bioengineering, mechanical engineering, chemistry, medicine, and relevant fields) to apply for the positions.
- Designing, fabrication (soft lithography), and characterization of microfluidic devices, lab-on-chip, organ-on-chip, 3D cellularity, tissue level in vitro modeling
- Cell seeding, cell culturing & maintaining on-chip; and investigating cell mechanics, cell-cell interactions, cell secretome, cell morphology on-chip
- Experience in developing tissue-level 3D mono/multi-cellular structure in vitro is a plus.
- Experience in organoids, stem cells, multicellular behaviors, cells in shear stress is a plus.
- We look for Immunology Researchers who can deepen our understanding of adaptive immunity and lymph node/lymphoid organ biology.
- Purification, adaptation, activation, and FACS characterization of immune cells (dendritic cells, T/B lymphocytes) obtained from animal and human samples.
- Monitoring immunity in vitro and in vivo.
- Modeling systemic/local infections in animal models and in vitro models.
- In vivo imaging (live or fixed samples) of immune cells and lymphoid organs in mice.
- Expertise in lymph nodes, lymphoid organs is a plus.
- We look for Molecular Biology Researchers who can deepen our mechanistic understanding of our findings.
- Knowledge and experience in cloning and genetic engineering in mammalian cells to generate knock-out or knock-in cells (e.g., CRISPR), and to visualize (e.g., GFP, RFP) specific proteins in the cells for live observation of the proteins.
- Experience in vascular, immune, cancer biology is a plus.
- We look for Organoid-based Tissue Engineers who can apply their technologies to host immunity, vascular, lymphatic, cancer, organ regenerative medicine.
- iPSCs differentiation to specific cell types (e.g. liver, gut, brain, heart, endothelial cells, pericytes, etc).
- Monitoring and characterizing organoid development in vitro and in vivo.
- We look for Cancer Biology Researchers who can deepen our understanding of tumor initiation, progression, interactions to blood and lymphatic vascular structures.
- Knowledge in mechanobiology of epithelial tumor cells is a plus
- Monitoring tumor interactions to vasculature in vitro and in vivo.
- Tumor immunotherapy, tumor metabolism, tumor metastasis, resistance.
- We look for Vascular Biology Researchers who can deepen the understanding of blood and lymphatic vascular morphogenesis, homeostasis, and pathogenesis.
- Purification, maintaining and culturing human blood/lymphatic vascular endothelial cells and vascular mural cells (pericytes, smooth muscle cells, etc) using animal and human samples.
- Monitoring vascular morphology and function in vitro and in vivo.
- Monitoring tumor/immune cell interactions to vasculatures in vitro and in vivo.
- Expertise in vivo implantation of engineered tissues is a plus.
- Expertise in vascular disease animal models in vivo (lymphedema, hypertension, vascular leakage, etc) is a plus.
How to apply:
Send your cover letter and current CV that includes your degree information, publications, and the list of 3 references to Dr. Lee.